Description
The Acquity UPC2 System utilises convergence chromatography, an extension to the capabilities of gas chromatography. It retains and elutes polar compounds last, offering the separation power of normal-phase liquid chromatography (LC) combined with the ease-of-use of reversed-phase LC.
The chromatography system uses green and non-toxic compressed liquid CO2 as the primary mobile phase, allowing precise variation of mobile phase strength, pressure, and temperature. This capability to fine-tune resolving power and selectivity enables better control over analyte retention, facilitating the separation, detection, and quantification of structural analogs, isomers, and enantiomeric and diastereomeric mixtures. These compounds often present significant challenges for separation by other methods.
UPC2 Column Manager 30S:
Designed to enable greater flexibility for the ACQUITY UPC2â„¢ and ACQUITY APCâ„¢ Systems
- 30cm Single Zone Column Manager
- Easy Removal/Replacement
- Capacity 8 Columns:
- Lengths 50mm to 300mm
- Internal Diameters 2.1mm to 8mm
- Integrated Passive Pre-Heating
- Stable Column Temperature
UPC2 Convergence Manager:
Regulates & monitors incoming flow and pressure of liquid CO2
- Electronically Controlled CO2 Inlet Shut-Off Valve
- Triggered by Power-Off or Error
- Overpressure Protection
- Auxillary Valve
- Venting Injection Loop
- Automated Back Pressure Regulator (ABPR)
- CO2 Pressure Relief
- Relieves Overpressure
- Vents to Waste or External CO2 Vent
- CO2 Inlet Pressure Transducer:
- Measurement Range -124 psi to 1190 psi
- Resolution 10 psi
- Accuracy +/- 30 psi
- Maximum Working Pressure 2000 psi
UPC2 Sample Manager FL:
Controls sample injections with fixed-loop injector. Regulates CO2 depressurisation in flow path
- Number of Sample Plates = Any 2 plates:
- 96 and 384 Microtiter Plates
- 48 Position 2.00mL Vial Plates
- 48 Position 0.65mL Microcentrifuge Tube Plates
- 24 Position 1.50mL Microcentrifuge Tube Plates
- Maximum Sample Capacity 768
- 2x 384-well plates
- Number of Sample Injections 1 to 99 Injections/Sample
- Injection Volume Range 0.1μl to 50μl
- 0.1μl Increments
- Sample Delivery Precision <1% RSD within 20% to 75% of Loop Volume for 10-uL loops, UV Detection
- Injector Linearity: >0.999 coefficient of deviation (from 20% to 75%)
- Sample Temperature Control 4°C to 40°C
- 0.1°C Increments
- Sample Probe: XYZZ Based Needle-in-Needle Design
- Minimum Sample 5 uL Residual
- Wash Solvents:
- 2 Degassed: Strong Solvent andWeak Wash Solvent
- Programmable to Suit Application
- Sample Carryover <0.005% or <2.000 nL
- Wetted Materials – See Data Sheet
UPLC ELS Detector:
The Evaporative Light Scattering (ELS) Detector offers unparalleled performance when monitoring compounds with poor to no ultraviolet/visible response and analytes that do not ionise well in mass spectrometry.
- Front-Mounted, Snap-In Design Nebuliser
- Nitrogen Gas >65 psi
- Heated Optics Bench 50°C
- Light Source:
- Tungsten Halogen Polychromatic
- Front-Mounted
- Pre-Aligned
- User Installable
- Photomultiplier Tube Detector
- Range 0.1 to 2000 Light Scattering Units
- Filter Settings:
- Hamming
- 0s to 5s
- 0.1s Increments
